Mano Horinaka Selected Research

BI D1870

3/2022

The Rationale for the Dual-Targeting Therapy for RSK2 and AKT in Multiple Myeloma.

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Mano Horinaka Research Topics

Disease

52	Neoplasms (Cancer) 02/2024 - 08/2004
11	Colonic Neoplasms (Colon Cancer) 03/2022 - 03/2007
10	Prostatic Neoplasms (Prostate Cancer) 02/2016 - 11/2004
5	Lung Neoplasms (Lung Cancer) 02/2024 - 01/2020
4	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2023 - 01/2020
4	Urinary Bladder Neoplasms (Bladder Cancer) 02/2018 - 02/2011
3	Colorectal Neoplasms (Colorectal Cancer) 11/2022 - 03/2007
3	Polyps 03/2022 - 11/2018
2	Breast Neoplasms (Breast Cancer) 10/2022 - 08/2018
2	Adenomatous Polyposis Coli (Familial Adenomatous Polyposis) 03/2022 - 01/2022
2	Hypoxia (Hypoxemia) 01/2022 - 02/2011
2	Triple Negative Breast Neoplasms 10/2021 - 08/2018
2	T-Cell Leukemia (Leukemia, T Cell) 03/2010 - 09/2007
2	Uterine Cervical Neoplasms (Cancer of the Cervix) 11/2005 - 08/2005
1	Ataxia Telangiectasia (Louis Bar Syndrome) 10/2023
1	Aberrant Crypt Foci 01/2023
1	Carcinogenesis 01/2023
1	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 10/2022
1	Multiple Myeloma 03/2022
1	Intestinal Polyps 03/2022
1	Genomic Instability 01/2022
1	Adenocarcinoma 01/2022
1	Adenoma (Adenomas) 01/2022
1	Adenocarcinoma of Lung 01/2020
1	Carcinoma (Carcinomatosis) 01/2020
1	Keloid 01/2017
1	Hemangiosarcoma (Angiosarcoma) 04/2015

Drug/Important Bio-Agent (IBA)

24	LigandsIBA 01/2023 - 07/2005
22	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2023 - 07/2005
10	Proteins (Proteins, Gene)FDA Link 10/2023 - 05/2005
10	TNF-Related Apoptosis-Inducing Ligand ReceptorsIBA 08/2014 - 08/2004
6	Messenger RNA (mRNA)IBA 01/2022 - 05/2005
6	Histone Deacetylase InhibitorsIBA 01/2020 - 08/2004
4	Tyrosine Kinase InhibitorsIBA 01/2023 - 12/2021
4	CytokinesIBA 01/2023 - 02/2010
4	YM753 compoundIBA 08/2018 - 10/2013
4	Histone Deacetylases (Histone Deacetylase)IBA 08/2018 - 04/2010
3	Antineoplastic Agents (Antineoplastics)IBA 02/2024 - 12/2008
3	Anaplastic Lymphoma KinaseIBA 01/2023 - 12/2021
3	Small Interfering RNA (siRNA)IBA 11/2022 - 12/2008
3	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 11/2022 - 01/2022
3	sulforaphaneIBA 10/2019 - 09/2006
3	Hormones (Hormone)IBA 02/2016 - 12/2008
3	FlavonoidsIBA 11/2008 - 11/2005
2	Lysine (L-Lysine)FDA Link 02/2024 - 10/2022
2	Phosphotransferases (Kinase)IBA 10/2023 - 03/2022
2	Carrier Proteins (Binding Protein)IBA 11/2022 - 11/2018
2	Vorinostat FDA Link 10/2022 - 08/2004
2	osimertinibIBA 01/2022 - 01/2020
2	EnzymesIBA 01/2022 - 01/2022
2	RO5126766IBA 10/2021 - 01/2014
2	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 10/2021 - 01/2014
2	eribulin FDA Link 10/2021 - 08/2018
2	Mechanistic Target of Rapamycin Complex 1IBA 11/2018 - 04/2015
2	SurvivinIBA 08/2018 - 10/2013
2	Anti-Obesity Agents (Antiobesity Drugs)IBA 02/2016 - 05/2012
2	Orlistat (Xenical)FDA Link 02/2016 - 05/2012
2	Butyric Acid (Butanoic Acid)IBA 01/2014 - 08/2004
2	TunicamycinIBA 11/2007 - 07/2005
2	LuteolinIBA 11/2005 - 08/2005
1	entinostat (MS 275)IBA 02/2024
1	lorlatinibIBA 01/2023
1	AzoxymethaneIBA 01/2023
1	AntioxidantsIBA 01/2023
1	ribosomal protein S3IBA 11/2022
1	Salicylic Acid (2 Hydroxybenzoic Acid)FDA LinkGeneric 11/2022
1	BuffersIBA 10/2022
1	ipatasertibIBA 03/2022
1	BI D1870IBA 03/2022
1	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 03/2022
1	Mesalamine (Mesalazine)FDA LinkGeneric 03/2022
1	Sodium Salicylate (Salicylate, Sodium)IBA 03/2022
1	Cyclin D1IBA 03/2022
1	VimentinIBA 01/2022
1	AfatinibIBA 01/2022
1	dacomitinibIBA 01/2022
1	Gefitinib (Iressa)FDA Link 01/2022
1	Glutathione (Reduced Glutathione)IBA 01/2022
1	Transcription Factors (Transcription Factor)IBA 01/2022
1	JNK Mitogen-Activated Protein KinasesIBA 12/2021
1	Cytotoxins (Cytolysins)IBA 10/2021
1	amrubicinIBA 01/2020
1	Apoptosis Regulatory ProteinsIBA 10/2019
1	Baculoviral IAP Repeat-Containing 3 ProteinIBA 10/2019
1	Voltage-Dependent Anion Channel 1IBA 11/2018
1	sulindac sulfone (exisulind)IBA 11/2018
1	spiruchostatin AIBA 02/2018
1	Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA 02/2018
1	infigratinibIBA 02/2018
1	Cisplatin (Platino)FDA LinkGeneric 02/2018
1	isothiocyanic acidIBA 01/2017
1	CollagenIBA 01/2017
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2017
1	Interleukin-6 (Interleukin 6)IBA 01/2017
1	CaspasesIBA 01/2016
1	Celecoxib (Celebrex)FDA Link 01/2016

Therapy/Procedure

29	Therapeutics 02/2024 - 08/2004
4	Chemoprevention 11/2018 - 09/2008
3	Drug Therapy (Chemotherapy) 02/2018 - 10/2013
1	Investigational Therapies (Experimental Therapy) 01/2016